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1.
Clinics (Sao Paulo) ; 79: 100321, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38301538

RESUMO

BACKGROUND: The oral cavity is a link between of external environment with gastrointestinal tract. Studies are controversial on the presence of Periodontal Disease (PD) and its association with Gastric Adenocarcinoma (GAC). METHODS: The authors performed a systematic review and meta-analysis to verify the association between PD and GAC. Six electronic databases were evaluated between 1961 and 2022. Titles and abstracts were reviewed independently according to the eligibility criteria, assessing full texts of selected studies. The quality of the included research was verified using the Newcastle-Ottawa Scale for case-control and cohort studies. Statistical analyses were performed based on fixed and/or random effects models to calculate the summarized Relative Risk (RR) and its 95 % Confidence Interval (95 % CI). RESULTS: There were 639 studies, of which nine articles were included (3 case-controls and 6 cohorts). Overall, the authors identified 1,253 cases of GAC 2,501 controls in case-control studies, and 1,631 patients with GAC enrolled in cohort studies. Patients presenting PD increased the risk of developing GAC by 17 % (RR=1.17; 95 % CI 1.03‒1.32), which remained regardless of the diagnostic method for PD, i.e., clinical examination (RR = 1.19; 95 % CI 1.14‒1.24) and self-report (RR = 1.34; 95 % CI 1.06‒1.69). Moreover, Asian patients (RR=1.17; 95 % CI 1.00‒1.36) with PD had a higher risk of having GAC than American and European patients (RR = 1.18; 95 % CI 0.84‒1.66). CONCLUSIONS: The presence of PD the risk of GAC suggesting that its infectious-inflammatory process of PD may be related to GAC development. Further investigations on the oral-gastric microbiota and its role in the carcinogenesis of gastric cancer should be carried out, and the screening of patients with potential risk for GAC should be considered in the clinical practice of dentists.


Assuntos
Adenocarcinoma , Doenças Periodontais , Neoplasias Gástricas , Humanos , Doenças Periodontais/complicações , Doenças Periodontais/epidemiologia , Estudos de Coortes , Estudos de Casos e Controles
2.
Clinics ; 79: 100321, 2024. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1534244

RESUMO

Abstract Background The oral cavity is a link between of external environment with gastrointestinal tract. Studies are controversial on the presence of Periodontal Disease (PD) and its association with Gastric Adenocarcinoma (GAC). Methods The authors performed a systematic review and meta-analysis to verify the association between PD and GAC. Six electronic databases were evaluated between 1961 and 2022. Titles and abstracts were reviewed independently according to the eligibility criteria, assessing full texts of selected studies. The quality of the included research was verified using the Newcastle-Ottawa Scale for case-control and cohort studies. Statistical analyses were performed based on fixed and/or random effects models to calculate the summarized Relative Risk (RR) and its 95 % Confidence Interval (95 % CI). Results There were 639 studies, of which nine articles were included (3 case-controls and 6 cohorts). Overall, the authors identified 1,253 cases of GAC 2,501 controls in case-control studies, and 1,631 patients with GAC enrolled in cohort studies. Patients presenting PD increased the risk of developing GAC by 17 % (RR=1.17; 95 % CI 1.03‒1.32), which remained regardless of the diagnostic method for PD, i.e., clinical examination (RR = 1.19; 95 % CI 1.14‒1.24) and self-report (RR = 1.34; 95 % CI 1.06‒1.69). Moreover, Asian patients (RR=1.17; 95 % CI 1.00‒1.36) with PD had a higher risk of having GAC than American and European patients (RR = 1.18; 95 % CI 0.84‒1.66). Conclusions The presence of PD the risk of GAC suggesting that its infectious-inflammatory process of PD may be related to GAC development. Further investigations on the oral-gastric microbiota and its role in the carcinogenesis of gastric cancer should be carried out, and the screening of patients with potential risk for GAC should be considered in the clinical practice of dentists.

3.
Am J Ind Med ; 66(12): 1090-1100, 2023 12.
Artigo em Inglês | MEDLINE | ID: mdl-37792286

RESUMO

OBJECTIVE: To investigate the association between occupation and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections within a Brazilian municipality. METHODS: In this test-negative study, cases and controls were randomly selected among individuals aged 18-65 years that were registered in a primary health care program in São Caetano do Sul, Brazil. Those who had collected samples for RT-PCR testing between April 2020 and May 2021 were randomly selected to compose the case (positive for SARS-CoV-2) and control (negative for SARS-CoV-2) groups, frequency-matched by sex, age group, and month of sample collection. Complementary data were collected through phone interviews. We estimated the residual effect of occupation on SARS-CoV-2 infection using multiple conditional logistic regression models incrementally adjusted for confounding variables. RESULTS: 1724 cases and 1741 controls who reported being at work at the time of RT-PCR collection were included. Cases were mainly females (52.9%), Whites/Asians (73.3%), and unvaccinated against COVID-19 (46.6%). Compared to other university-level professionals, the highest odds of having COVID-19 were found for workers in police and protective services (odds ratio [OR] 2.21; 95% confidence interval [CI] 1.27-3.84), healthcare and caregiving (OR 1.90; 95% CI 1.34-2.68), and food retail and production (OR 1.88; 95% CI = 1.14-3.11), after adjustment for age, sex, education, means of transport, household crowding, and COVID-19 vaccination. CONCLUSION: Occupation played an important role in SARS-CoV-2 infection. Food retail and production, health care and caregiving, and police and protective services showed the highest odds of SARS-CoV-2 infection.


Assuntos
COVID-19 , Feminino , Humanos , Masculino , COVID-19/epidemiologia , SARS-CoV-2 , Brasil/epidemiologia , Estudos de Casos e Controles , Vacinas contra COVID-19 , Aglomeração , Características da Família , Ocupações
4.
Head Neck ; 45(9): 2377-2393, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37401537

RESUMO

BACKGROUND: We investigated whether the socioeconomic status (SES) influenced survival rates in oropharynx cancers (OPC), oral cavity cancers (OCC), and larynx cancers (LC) in Brazilian patients. METHODS: This hospital-based cohort study assessed the age-standardized 5-year relative survival (RS) using the Pohar Perme estimator. RESULTS: Overall, we identified 37 191 cases, and 5-year RS were 24.4%, 34.1%, and 44.9% in OPC, OCC, and LC, respectively. In multiple Cox regression, the highest risk of death occurred in the most vulnerable social strata for all subsites-that is, illiterates or patients relying on publicly funded healthcare services. Disparities increased over time by 34.9% in OPC due to the rising of survival rates in the highest SES, whereas they reduced by 10.2% and 29.6% in OCC and LC. CONCLUSIONS: The potential inequities were more significant for OPC than for OCC and LC. It is urgent to tackle social disparities to improve prognoses in highly unequal countries.


Assuntos
Neoplasias de Cabeça e Pescoço , Neoplasias Laríngeas , Neoplasias Bucais , Neoplasias Orofaríngeas , Humanos , Estudos de Coortes , Neoplasias de Cabeça e Pescoço/terapia , Classe Social , Neoplasias Laríngeas/terapia
5.
PLoS One ; 18(5): e0285975, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37228121

RESUMO

OBJECTIVE: We investigated the impact of socioeconomic inequalities on chronic pain of older adults according to sex. MATERIALS AND METHODS: This population-based cross-sectional study used survey data from the 2015 cohort of the SABE Study (Saúde, Bem-estar e Envelhecimento), Brazil. Socioeconomic status was examined at individual level (educational attainment, financial independence, and race/skin color) and contextual level (Human Development Index). We analyzed the association between variables using the chi-square test and the Rao & Scott correction. Logistic regression models were adjusted for risk factors. RESULTS: The study comprised 1,207 older adults representing 1,365,514 residents 60≥ years of age in the city of São Paulo. Chronic pain was more frequent in females (27.2%) than in males (14.5%) (p<0.001). Females evidenced the worst self-perception of pain, especially those of the most vulnerable socioeconomic strata. Social inequalities impacted chronic pain in different ways between sexes. Among females, unfavorable living conditions (OR = 1.59; 95%CI 1.07; 2,37) and Blacks/Browns females were most likely to have chronic pain (OR = 1.32; 95%CI 1.01; 1.74). Among males, only the individual aspects were significant for the occurrence of chronic pain, such as low educational attainment (OR = 1.88; 95%CI 1.16; 3.04) and insufficient income (OR = 1.63; 95%CI 1.01; 2.62). DISCUSSION: The potential for inequality was greater for females than for males reflecting structural factors inherent in a highly unequal society. Conclusions: Equity-oriented health policies are critical to preventing pain in human aging.


Assuntos
Dor Crônica , Masculino , Feminino , Humanos , Idoso , Estudos Transversais , Dor Crônica/epidemiologia , Brasil/epidemiologia , Fatores Socioeconômicos , Classe Social
6.
Cad Saude Publica ; 38(1): e00254220, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35081205

RESUMO

Although São Paulo is the most populous city in Brazil - one of the world's most violent countries - a significant reduction in its homicide mortality rate (HMR) has been detected. This study aims to estimate the effects of age, period, and birth cohort on the trend of homicide mortality according to sex in the city of São Paulo, from 1996 to 2015. An ecological study was undertaken with data on deaths by homicide for both sexes, in all age brackets, in the city of São Paulo. Poisson models were adjusted for each sex to estimate the age-period-cohort effects. In total, 61,833 deaths by homicide were recorded among males and 5,109 among females. Regardless of the period, the highest HMR occurred in the 20-24 age bracket. Higher HMRs were found in those born in the 1970s and 1980s. The complete model, with age-period-cohort effects, were the best fit to the data. The risk of death by homicide declined over the periods, with lower intensity in the final five years (2011-2015), for both males (RR = 0.48; 95%CI: 0.46; 0.49) and females (RR = 0.52; 95%CI: 0.47; 0.57). A reduction was found in the risk of homicide, regardless of the sex or age bracket, and also in recent cohorts. However, the intensity of such reductions has been decreasing over time, which suggests that the public policies adopted have limited potential to maintain these achievements.


Assuntos
Coorte de Nascimento , Homicídio , Brasil/epidemiologia , Cidades , Efeito de Coortes , Feminino , Humanos , Masculino , Mortalidade
7.
Cad. Saúde Pública (Online) ; 38(1): e00254220, 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1355990

RESUMO

Abstract: Although São Paulo is the most populous city in Brazil - one of the world's most violent countries - a significant reduction in its homicide mortality rate (HMR) has been detected. This study aims to estimate the effects of age, period, and birth cohort on the trend of homicide mortality according to sex in the city of São Paulo, from 1996 to 2015. An ecological study was undertaken with data on deaths by homicide for both sexes, in all age brackets, in the city of São Paulo. Poisson models were adjusted for each sex to estimate the age-period-cohort effects. In total, 61,833 deaths by homicide were recorded among males and 5,109 among females. Regardless of the period, the highest HMR occurred in the 20-24 age bracket. Higher HMRs were found in those born in the 1970s and 1980s. The complete model, with age-period-cohort effects, were the best fit to the data. The risk of death by homicide declined over the periods, with lower intensity in the final five years (2011-2015), for both males (RR = 0.48; 95%CI: 0.46; 0.49) and females (RR = 0.52; 95%CI: 0.47; 0.57). A reduction was found in the risk of homicide, regardless of the sex or age bracket, and also in recent cohorts. However, the intensity of such reductions has been decreasing over time, which suggests that the public policies adopted have limited potential to maintain these achievements.


Resumo: Embora São Paulo seja a cidade mais populosa do Brasil, que é um dos países mais violentos do mundo, o município vem apresentando uma redução significativa na taxa de mortalidade por homicídio (TMH). O estudo buscou estimar os efeitos de idade, período e coorte de nascimentos na tendência da mortalidade por homicídio de acordo com sexo na cidade de São Paulo, entre 1996 e 2015. Foi realizado um estudo ecológico com dados sobre óbitos por homicídio em ambos os sexos, em todas as faixas etárias, no local e período mencionados acima. Foram ajustados modelos de Poisson para cada sexo, para estimar os efeitos de idade-período-coorte. Foram registrados 61.833 óbitos por homicídio em homens e 5.109 em mulheres. Independentemente do período, a TMH mais alta ocorreu na faixa etária de 20-24 anos. As TMH mais altas foram observadas em indivíduos que nasceram nas décadas de 1970 e 1980. O melhor ajuste para os dados foi como o modelo completo, com os efeitos de idade-período-coorte. O risco e óbitos por homicídio diminuiu ao longo dos anos, com a menor intensidade nos últimos cinco anos (2011-2015), tanto em homens (RR = 0,48; IC95%: 0,46; 0,49) quanto em mulheres (RR = 0,52; IC95%: 0,47; 0,57). Foi observada uma redução no risco de homicídio, independente de sexo ou faixa etária, como também, nas coortes mais recentes. Entretanto, a intensidade dessas reduções tem diminuído ao longo do tempo, sugerindo que as políticas públicas adotadas têm potencial limitado para manter os avanços alcançados.


Resumen: A pesar de que São Paulo es la cuidad más poblada en Brasil, uno de los países más violentos del mundo, ha estado mostrando una significativa reducción en su tasa de mortalidad por homicidios (TMH). Este estudio se propone estimar los efectos de la edad, período, y cohorte de nacimiento sobre la tendencia de la mortalidad por homicidio, según sexo, en la ciudad de Sao Paulo, de 1996 a 2015. Se realizó un estudio ecológico con datos sobre las muertes por homicidio en ambos sexos, en todos los grupos de edad, en el lugar y período mencionado previamente. Con el fin de estimar los efectos de la edad-período-cohorte, se ajustaron modelos Poisson para ambos sexos. Se registraron un total de 61.833 muertes por homicidio entre hombres y 5.109 entre mujeres. Independientemente del período, la TMH más alta se produjo en la franja de edad 20-24. Unas TMH más altas se observaron en quienes habían nacido en los 1970 y los 1980. El modelo completo, con los efectos edad-período-cohorte, fue la mejor manera de ajustar los datos. El riesgo de muerte por homicidio se redujo a lo largo de los períodos, con una intensidad más baja en los últimos cinco años (2011-2015), para tanto hombres (RR = 0,48; IC95%: 0,46; 0,49), como mujeres (RR = 0,52; IC95%: 0,47; 0,57). Se observó una reducción en el riesgo de homicidio, independientemente del sexo o franja de edad, así como en las cohortes recientes. No obstante, la intensidad de tales reducciones ha estado decreciendo a lo largo del tiempo, lo que sugiere que las políticas públicas adoptadas tienen un potencial limitado para mantener estos logros.


Assuntos
Humanos , Masculino , Feminino , Homicídio , Brasil/epidemiologia , Efeito de Coortes , Mortalidade , Cidades
8.
Oral Oncol ; 115: 105177, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33561611

RESUMO

In head and neck cancer (HNC), some subsites are associated with human papillomavirus (HPV) infection, whereas others are unrelated. Although studies have demonstrated the heterogeneity of HPV prevalence worldwide, its impacts on incidence trends in HNC are unknown. This systematic review examined the incidence trends for HPV-related HNC subsites, exploring patterns by geographic region, age group, sex, and race/ethnicity. We searched for publications on PubMed, Embase, and Scopus. Eligible articles included population-based studies that analyzed incidence trends for subsites classified as a proxy for HPV infection in HNC (hereafter referred to as HPV-related subsites). We retrieved 3,948 non-duplicate records, of which 31 were eligible articles, representing 18 countries and spanning almost fifty years. Overall, the incidence of HPV-related HNC subsites rose, while most of the HPV-unrelated subsites declined or remained stable. For HPV-related HNC subsites, incidence trends increased regardless of age group, highlighting a distinct global pattern between sexes. Also, similar peaks in increased risk were observed in recent cohorts from both Australia and the United States. There is a dramatic shift in the global trends of HNCs, characterized by the emerging burden in HNC for HPV-related subsites.


Assuntos
Neoplasias de Cabeça e Pescoço/epidemiologia , Infecções por Papillomavirus/virologia , Feminino , Humanos , Incidência , Masculino
9.
Sci Rep ; 10(1): 19164, 2020 11 05.
Artigo em Inglês | MEDLINE | ID: mdl-33154465

RESUMO

The present study was conducted to evaluate the socioeconomic inequality related to lung cancer mortality rates and trends between 2000 and 2015 according to gender in Brazil. We retrieved the death records for cases of lung cancer (ICD-10 C33 C34) from 2000 to 2015 in adults age 30 years and older in Brazilian Regions from official databases (DATASUS) and corrected for ill-defined causes. The Prais-Winsten regression method and Pearson correlation were applied. The results were considered statistically significant when p < 0.05. The correlation between the lung cancer mortality rates and the HDI decreased when the rates for the first and last years of the historical series were compared in men (r = 0.77; r = 0.58) and women (r = 0.64; r = 0.41). However, the correlation between the trends in the lung cancer mortality rates and the HDI was negative in men (r = - 0.76) and women (r = - 0.58), indicating larger reductions (or smaller additions) among the Federative Units with the highest HDI, in contrast to trends reflecting a greater increase in those with the lowest HDI. Our results suggest a relevant inequality in the trends of mortality from lung cancer in Brazil.


Assuntos
Neoplasias Pulmonares/mortalidade , Adulto , Idoso , Idoso de 80 Anos ou mais , Brasil/epidemiologia , Feminino , Disparidades nos Níveis de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Mortalidade/tendências , Fatores Sexuais , Fatores Socioeconômicos
10.
PLoS One ; 15(5): e0232871, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32407339

RESUMO

Human papillomavirus (HPV) is responsible for the rise in the incidence of cancer in the oropharynx, tonsils, and base of the tongue (i.e., HPV-related subsites). HPV triggered the changes in the epidemiology of oropharyngeal and oral cavity cancer (OPC/OCC) in Asia, Europe, North America, and Oceania. Hence, the incidence of cancer in HPV-related subsites is augmenting, while that in other HPV-unrelated subsites is decreasing. In South America, although the incidence of HPV-positive tumors has gradually increased, there is an atypically low prevalence of HPV in people with OPC/OCC. To clarify whether this dramatic shift in incidence trends also occurred in this population, we estimated the burden of HPV on the incidence trends of OPCs/OCCs in São Paulo city in Brazil. In this population-based study, we categorized OPCs/OCCs by HPV-related and HPV-unrelated subsites. We used Poisson regression to assess the age-standardized incidence rates (ASRs) stratified by sex and age groups, as well as to examine the age-period-cohort effects. There were 15,391 cases of OPCs/OCCs diagnosed in HPV-related (n = 5,898; 38.3%) and HPV-unrelated (n = 9,493; 61.7%) subsites. Overall, the ASRs decreased for most subsites, for both sexes and for all age groups, except for HPV-related OPC/OCC in young males and females, which increased by 3.8% and 8.6% per year, respectively. In the birth-cohort-effect analysis, we identified an increasing risk for HPV-related OPC/OCC in both sexes in recent birth cohorts; however, this risk was sharply decreased in HPV-unrelated subsites. Our data demonstrate an emerging risk for HPV-related OPC/OCC in young people, which supports prophylactic HPV vaccination in this group.


Assuntos
Carcinoma de Células Escamosas/epidemiologia , Neoplasias Bucais/epidemiologia , Neoplasias Orofaríngeas/epidemiologia , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/complicações , Adolescente , Adulto , Fatores Etários , Idoso , Brasil/epidemiologia , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/virologia , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/patologia , Neoplasias Bucais/virologia , Neoplasias Orofaríngeas/patologia , Neoplasias Orofaríngeas/virologia , Infecções por Papillomavirus/virologia , Fatores de Risco , Fatores Sexuais , Adulto Jovem
11.
São Paulo; s.n; 2020. 197 p.
Tese em Português | LILACS | ID: biblio-1120939

RESUMO

Introdução: Estudos laboratoriais e epidemiológicos demonstraram uma epidemia viral no câncer de cabeça e pescoço (CCP) relacionada ao papilomavírus humano (HPV). Entretanto, não está claro se esse aumento na incidência afeta igualmente as populações e seus subgrupos ou se essa epidemia viral se limita a países específicos. Por tais motivos, investigou-se a epidemiologia do câncer de boca, orofaringe e laringe segundo a relação com o HPV. Métodos: A tese compreende três manuscritos: (i) uma revisão sistemática sobre as tendências de incidência globais do CCP segundo sítios anatômicos associados ao HPV; (ii) um estudo de base populacional prévio à implementação da vacina para o HPV no município de São Paulo (1997-2013), analisando as tendências de incidência e o efeito idade-período-coorte do CCP estratificado por localizações anatômicas HPV-relacionadas; e (iii) um estudo de base hospitalar sobre a influência do HPV e das iniquidades sociais na sobrevida por CCP dos pacientes do estado de São Paulo (2000-2018). Resultados: No primeiro artigo, confirmou-se a hipótese de que há uma mudança significativa nas tendências de incidência globais de CCPs devido à carga emergente nos sítios anatômicos HPVrelacionados. Em geral, as tendências de incidência padronizadas por idade, ou agestandardized rate (ASRs), aumentaram em localizações anatômicas HPVrelacionadas. Porém, as ASRs diminuíram para os CCPs relacionados ao consumo de álcool e tabaco. No segundo artigo, analisou-se 15.391 cânceres de boca e orofaringe (CBO). Para tanto, observou-se um aumento nas ASRs em localizações anatômicas HPV-relacionadas em mulheres (8,6%/ano) e homens (3,8%/ano) com idade <=39 anos. Ademais, houve um risco crescente nas coortes de nascimento em ambos os sexos no CBO HPV-relacionado, enquanto o risco reduziu no CBO HPVnão relacionado. No terceiro artigo, investigou-se a sobrevida em sítios anatômicos HPV-relacionados (n= 12.238), no câncer de boca (n= 12.858) e laringe (n = 12.095), sendo a net survival ajustada por idade em cinco anos de 24,4%, 34,1% e 44,9%, respectivamente. Independentemente da relação do sítio anatômico com o HPV, o maior risco de morte ocorreu nos estratos sociais mais vulneráveis (i.e., analfabetos ou pacientes com assistência pública de saúde), ajustando-se por faixa etária, sexo, estadiamento clínico e tratamentos (cirurgia, quimioterapia e radioterapia). As disparidades na sobrevida aumentaram em 34,9% em sítios anatômicos HPVrelacionados, enquanto houve uma redução de 10,2% e 29,6% no câncer de boca e laringe. Considerações finais: Existe um aumento na carga dos CCPs HPVrelacionados no Brasil e no mundo. Portanto, tem-se a recomendação do uso profilático da vacina para o HPV em ambos os sexos e o desenvolvimento de políticas públicas para proporcionar justiça social no acesso universal à saúde.


Introduction: Molecular and epidemiological findings have demonstrated a "virusrelated cancer epidemic" in head and neck cancer (HNC) caused by the human papillomavirus (HPV) infection. However, it is unclear whether this increasing incidence affects populations and their subgroups likewise, or whether it is restricted to certain countries. This investigation assessed the epidemiology of oral cavity cancers (OCC), oropharyngeal cancers (OPC), and larynx cancers (LC) according to HPV-related subsites. Methods: This thesis includes three manuscripts: (i) The systematic review focusing on global incidence trends in HNCs according to HPVrelated subsites; (ii) The population-based study previous to prophylactic HPV vaccinations introduction in the city of São Paulo (1997-2013), which assessed incidence trends and age-period-cohort effect; and (iii) The hospital-based cohort study on the impact of HPV and inequalities on the survival of patients diagnosed with HNC in the state of São Paulo (2000-2018). Results: In the first study, we confirmed the hypothesis on the significative change in global incidence trends in HNCs due to the emerging burden of cancers in HPV-related subsites. Overall, age-standardized incidence rates (ASR) increased in HPV-related subsites. Conversely, ASRs decreased in HNCs associated with alcohol and tobacco use. In the second study, we analyzed 15,391 cases of OCC and OPC. Hence, we found an upward incidence trend in HPV-related subsites in females and males aged <=39 years of 8.6% and 3.8% per year, respectively. Furthermore, there was an emerging risk in recent birth cohorts in both sexes in HPV-related OCC/OPC, whereas the risk reduced in HPV-unrelated OCC/OPC. In the third study, we assessed the survival in HPV-related subsites (n= 12,238), OCC (n= 12,858), and LC (n= 12,095). These subsites had an agestandardized 5-year relative survival (RS) of 24.4%, 34.1%, and 44.9%, respectively. For all subsites, we found the highest hazard of death in the most vulnerable social strata - i.e., illiterates or public funded healthcare patients, adjusted for age group, sex, clinical staging, and treatments (chemotherapy, radiotherapy, and surgery). Survival inequalities rose 34.9% in HPV-related subsites, whereas it diminished in OCC and LC by 10.2% and 29.6%, respectively. Conclusions: There is an increasing burden in HPV-related HNCs in Brazil and the world. Therefore, we recommend prophylactic HPV vaccination use in both sexes, as well as public policies to ensure social justice in universal healthcare access.


Assuntos
Orofaringe , Papillomaviridae , Sobrevida , Neoplasias Bucais , Neoplasias Laríngeas , Neoplasias de Cabeça e Pescoço
12.
Rev. bras. odontol ; 67(1): 106-110, jul.-dez. 2010. ilus, tab, graf
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-563847

RESUMO

Este artigo aborda 18 casos de fibroma ossificante periférico (FOP) diagnosticados no Centro de Referência de Lesões Bucais da Universidade Estadual de Feira de Santana/Bahia, no período de 2002 a 2008. Para descrever a relação entre as variáveis sociodemográficas com o FOP, utilizou-se o Statistical Package for Social Science (SPSS), versão 10.0 for Windows (1998). Observou-se maior acometimento desta doença na quarta década de vida, sexo feminino e cor não branca. A gengiva superior anterior foi a região de maior prevalência. Faz-se importante que os cirurgiões-dentistas conheçam as características do FOP para o correto diagnóstico.


Assuntos
Humanos , Fibroma Ossificante/epidemiologia , Patologia Bucal , Distribuição por Idade e Sexo
13.
Rev. ABENO ; 8(2): 160-166, 2008. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-859605

RESUMO

O presente trabalho discute as novas práticas desenvolvidas na disciplina de Odontologia Preventiva e Social I (OPS I) do curso de Odontologia da UEFS, em consonância com as Diretrizes Curriculares Nacionais (DCN) para o curso de Odontologia e às Políticas de Saúde Bucal no SUS, junto aos estudantes e profissionais da área de educação e de saúde . Utilizando-se uma concepção problematizadora no processo de ensino-aprendizagem, o estágio curricular, sob orientação docente, tem aproximado os discentes da realidade que compõe as Unidades de Saúde da Família (USF) . Tal fato possibilita aos discentes e professores: a) vivenciarem a rotina e a prática do serviço de saúde; b) realizarem ações de promoção de saúde, com abordagem sobre os fatores de risco ou proteção para doenças da boca e outros agravos; c) acompanharem visitas domiciliares e atividades de educação em saúde, envolvendo Equipes de Saúde da Família, de Saúde Bucal e comunidade. O território de atuação das Equipes de Saúde da Família (ESF) tem se constituído como cenário de formação dos profissionais de saúde, o que permite aos graduandos integrarem ações junto ao serviço e à comunidade, proporcionando aos mesmos a compreensão do processo de trabalho da ESF e a importância do conhecimento da realidade social da população como determinante da saúde geral e bucal . Esta estratégia visa, além da formação de um excelente técnico, um profissional generalista, com amplo conhecimento científico, sensível, que saiba cuidar, acolher e ouvir o usuário, responsabilizando-se por sua saúde (AU).


This paper discusses the new practices developed in the discipline of Preventive and Social Dentistry I (OPS I) of the UEFS Dentistry Course according to the National Curriculum Guidelines (DCN) for Den- tistry Courses and Oral Health Policies of the SUS, in relation to students and professionals of the education and health areas. Using a problematizing approach to the teaching-learning process, curricular internship under teacher guidance has brought students closer to the reality that makes up the Family Health Units (USF). This fact makes it possible for students and professors a) to experience the routine and practice of the health service, b) to carry out actions to promote health with an approach focusing on risk factors or protection against diseases of the mouth and other aggravations, and c) to monitor home visits and activities in health education involving Family Health Teams, oral health and the community. The locus of operation of the Family Health Teams (ESF) has become the area of training of the health professionals, thus allowing students to inte- grate actions in their services and in the community, thus giving them an understanding of the ESF work process and the importance of knowing the social reality of the population as a determinant of general and oral health . This strategy aims not only at training excellent technicians, but also at training a generalist professional with broad scientific knowledge, who is sensitive, who knows how to care, welcome and listen to patients, and who feels responsible for their health (AU).


Assuntos
Educação em Odontologia , Desenvolvimento de Pessoal , Estudantes de Odontologia , Brasil
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